Sashko DamjanovskiWestern Science
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    2023 lab

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    2018 lab

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    2017 lab

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    Summer 2017

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    2016 Lab

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    2014 Lab

The Damjanovski lab uses cultured cells to investigate secreted enzymes and how they regulate cell migration, invasion and cell-cell interactions. These enzymes (MMPs) and their inhibitors (TIMPs and RECK), which play crucial roles in many developmental processes, are often unregulated in diseases such as cancer. We use a number of cellular and molecular techniques to understand how MMPs are regulated in both development and disease. The lab has a myriad of tools, resources, and equipment that is common to most labs that undertake molecular biology experiments (PCR, Western blotting), and those specific to MMP studies (zymography, migration and invasion assays and 3D cell culture).  While we have much of our own equipment, many large items and imaging equipment are part of core shared facilities (MGU core, MoBEEs, Biotron).