Robert Hudson
Contact Information
Title: Professor
Office: Rm 222 ChB
Labs: 200 & 201 ChB
Phone (Office): ext 86349
E-mail: rhhudson@uwo.ca
Organic Teaching Division
Chemical Biology and Biomaterials
Synthetic and Bioorganic Chemistry of Nucleic Acids and Peptides
AWARDS
- Faculty Scholar 2010-2012
- USC Bank of Nova Scotia Alumni Award of Excellence in Undergraduate Teaching 2009-2010
- President's Occupational Health & Safety Award, 2008
- University Students' Council Teaching Honour Roll 2006-2007
- CNC-IUPAC Award, 2004
RESEARCH
Our principle research activities involve the application of organic synthesis in the field of bio-organic chemistry. We specialize in oligonucleotide analogs and our work is focused on peptide nucleic acid or PNA and nucleobase-modified DNA and RNA with special interest in fluorescent analogs.
For more information about the group please visit our research group homepage.
TEACHING
- 2213 - Organic Chemistry for Life Sciences
- 2223 - Organic Chemistry of Biological Molecules
- 2273 - Organic Chemistry I: Structure and Spectroscopy
- 3393 - Medicinal Chemistry
- 4493 - Chemistry of Biological Macromolecules
- 9520 - Advanced Nucleic Acid Chemistry
- 9553 - Mechanistic Organic Chemistry
SELECTED PUBLICATIONS
- Zi Wang, Morgan T. Tamminga, Paul Winiarz, James A. Wisner, Robert H. E. Hudson, “Organic-Soluble Cytosine Derivatives for Studying Base-Pair Interactions in Nonaqueous Solution” Can J. Chem. 2023, accepted for publication. (Special issue highlighting Excellence in Canadian Undergraduate Chemistry Research)
- Mria Chowdhury, Julia A. Turner, Daniela Cappello, Maryam Hajjami, Robert H. E. Hudson, “Chimeric GFP-uracil based molecular rotor fluorophores” Org. Biomol. Chem., 2023.
- Gyeongsu Park, Christie Ettles, McKenry Charles, Robert H. E. Hudson, “Nucleobase intrinsic quenchers: A fluorescence off switch” J. Photochem. Photobiol., A, 2023, 441, 114653.
- Mria Chowdhury, Robert H. E. Hudson, “Exploring Nucleobase Modifications in Oligonucleotide Analogues for Use as Environmentally Responsive Fluorophores and Beyond” Chem. Rec., 2023, 23, e202200218.
- Jeremie Mitteaux, Sandy Raevens, Zi Wang, Marc Pirrotta, Ibai Valverde, Robert Hudson, David Monchaud “PhpC modulates G-quadruplex-RNA landscapes in human cells” Chem. Commun. 2023.
- Jeremie Mitteaux, Pauline Lejault, Filip Wojciechowski, Alexandra Joubert, Julien Boudon, Nicolas Desbois, Claude P. Gros, Robert H. E. Hudson, Jean-Baptiste Boule, Anton Granzhan, David Monchaud, “Identifying G-Quadruplex-DNA-Disrupting Small Molecules” J. Am. Chem. Soc., 2021, 143, 12567- 12577.
